Obesity is a constantly growing health concern in the UK—recent data shows that 29 per cent of adults in England are living with obesity, and 64 per cent are either overweight or obese. Many are exploring treatments such as Wegovy and Mounjaro.
If you are using Wegovy and wondering whether you can change to Mounjaro, you are not alone. Both treatments are weight-loss injections, but they work slightly differently. Many people ask if switching from Wegovy to Mounjaro is safe, what happens during the transition, and whether the side effects are any different. Our pharmacists can help you understand your options and guide you through the process.
Can You Switch from Wegovy to Mounjaro?
Yes, it is possible to switch from Wegovy to Mounjaro if your treatment plan allows for it. Wegovy contains semaglutide, a GLP-1 receptor agonist that helps reduce appetite and regulate blood sugar. Mounjaro contains tirzepatide, which activates both GLP-1 and GIP receptors. This dual action may lead to greater weight-loss results for some patients, as shown in clinical trials.
Pharmacists usually consider switching when:
- You are not achieving the weight-loss results expected with Wegovy.
- You are experiencing side effects that may be better managed on Mounjaro.
- Your treatment goals have changed, and a different option is more suitable.
Before making any change, you should always have a consultation to ensure the transition is safe for you.
Transitioning from Wegovy to Mounjaro
The process is not always as simple as stopping one and starting the other. Our pharmacist may recommend a short gap or a specific starting dose of Mounjaro, depending on your history with Wegovy. This helps to reduce the risk of side effects and ensures your body adjusts gradually.
Wegovy vs Mounjaro Side Effects
Both medicines can cause digestive issues such as nausea, constipation, or diarrhoea. These are usually mild and improve over time. Serious side effects are rare but may include inflammation of the pancreas or gallbladder problems.
Some people switching from Wegovy to Mounjaro notice that side effects differ in intensity. Because Mounjaro works on two hormone pathways, it can sometimes increase feelings of fullness more strongly, which may affect how your stomach tolerates food in the first few weeks.
What Are the Benefits of Switching from Wegovy to Mounjaro?
The main benefit of switching from Wegovy to Mounjaro is the possibility of stronger results. In studies, patients taking tirzepatide (Mounjaro) often lost more weight compared to those on semaglutide (Wegovy). However, results vary from person to person.
Improved Weight-Loss Outcomes
For those who did not respond well to Wegovy, moving to Mounjaro could provide another chance to reach their goals. Some real-world reviews suggest people feel less hungry on Mounjaro compared to Wegovy.
Different Dosing and Tolerance
Wegovy is taken weekly with set dose increases. Mounjaro also uses a weekly injection but comes with a different titration plan. For some, this gradual approach feels easier to tolerate.
Are There Any Risks Involved?
Changing treatments always carries some risks, mainly around side effects and how your body adapts. If you stop Wegovy and move to Mounjaro too quickly, you may notice stronger side effects. Missing doses or not following the dosing plan can also reduce effectiveness.
It is important that any change is supervised by a qualified pharmacist, who can answer your questions and monitor your progress.
When to Seek Advice Urgently
If you experience severe stomach pain, signs of dehydration, or sudden changes in blood sugar, you should seek expert help immediately. While these reactions are rare, they need to be taken seriously.
Getting Professional Advice Before Making the Switch
If you are considering switching from Wegovy to Mounjaro, our pharmacists are here to guide you. We can review your current treatment, explain what to expect during the transition, and help you achieve the best results safely.
Book your appointment with our pharmacists at Touchwood Pharmacy today to discuss safe and effective weight-loss treatments personalised to your needs.
FAQs on Switching from Wegovy to Mounjaro
Is it safe to switch from Wegovy to Mounjaro?
Yes, switching can be safe if done under the guidance of a qualified pharmacist. A consultation is needed to review your medical history, current dosage, and any side effects before moving from Wegovy to Mounjaro.
Do I need to stop Wegovy completely before starting Mounjaro?
In some cases, yes. Depending on your last dose of Wegovy, our pharmacist may advise a short gap before beginning Mounjaro. This helps reduce the risk of stronger side effects when transitioning.
How soon will I notice results after switching to Mounjaro?
Many people start to feel appetite changes within the first few weeks. However, noticeable weight-loss results usually take several months and vary depending on your diet, lifestyle, and how your body responds.
Are the side effects different when moving from Wegovy to Mounjaro?
Both treatments can cause nausea, constipation, or diarrhoea. Some patients report that Mounjaro feels stronger at the start because it works on two hormone pathways. These effects often improve as your body adjusts.
What happens if I don’t respond well to Wegovy but also struggle with Mounjaro?
If you have difficulties with both, our pharmacist may suggest adjusting the dose or exploring other licensed weight-loss treatments. Regular follow-up appointments are important to make sure you are on the most suitable plan.
Can I switch from Wegovy to Mounjaro if I have type 2 diabetes?
Yes. Mounjaro is licensed in the UK for treating type 2 diabetes, and it is also authorised for weight management in eligible adults who are obese or overweight with related health conditions. If you are considering switching, it should be done following a consultation with a qualified pharmacist.
