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How Does Wegovy Compare to Other Weight Loss Treatments?

how wegovy compares with other popular weight loss treatments

Losing weight is challenging, and with rising obesity rates in the UK, choosing the right treatment is more important than ever. In 2023-24, 64.5% of adults in England were estimated to be either overweight or living with obesity — and 26.5% were living with obesity alone.

Wegovy weight loss injections have rapidly gained attention, but how do they compare with other treatments like Mounjaro or traditional medicines? Our pharmacists explain how Wegovy works, how it differs from rival options, and what factors you should weigh before considering this route.

What are Wegovy weight loss injections, and how do they work?

Wegovy contains semaglutide, a medicine that mimics a natural hormone called GLP-1. This hormone helps regulate appetite and food intake, which can lead to gradual and sustained weight loss. Wegovy is injected once a week using a pre-filled pen and is licensed in the UK for adults living with obesity or who have a weight-related condition such as high blood pressure or type 2 diabetes.

How Wegovy helps with weight loss

  • Slows how quickly food leaves the stomach, helping you feel full for longer
  • Reduces hunger signals to the brain
  • Supports steady calorie control over time

Clinical studies have shown that people using Wegovy alongside lifestyle changes can lose around 15% of their body weight over 68 weeks, on average.

How does Wegovy compare with other weight loss treatments?

Several medicines can support weight management, but they work in different ways. Understanding the main differences can help you make an informed choice.

Mounjaro vs Wegovy – what’s the difference?

Mounjaro (tirzepatide) and Wegovy (semaglutide) are both injectable treatments that target appetite-related hormones, but Mounjaro activates two hormone pathways—GLP-1 and GIP—which may provide greater blood-sugar control and appetite suppression.

Early studies suggest Mounjaro may lead to slightly higher average weight loss, but both medicines are highly effective when used correctly.

Is Mounjaro better than Wegovy?

It depends on individual response and suitability. Some people tolerate one injection better than the other. Both Wegovy and Mounjaro are now available in the UK through licensed pharmacies and specialist weight management services, although availability can vary depending on stock and prescription eligibility. Our pharmacists can advise which option best matches your medical history and goals.

Other prescription options

  • Orlistat: Works in the gut to block fat absorption but can cause digestive side effects.
  • Saxenda: Another GLP-1 injection used daily instead of weekly.
  • Metformin: Used mainly for blood-sugar control but may modestly aid weight loss in some people. 

Each treatment has its own benefits, so professional guidance is essential before starting.

What are the side effects of Wegovy?

Like most medicines, Wegovy can cause side effects, though not everyone experiences them. Common effects include:

  • Nausea or vomiting (especially during dose increases)
  • Constipation or diarrhoea
  • Headache or tiredness

These often improve as your body adjusts. Serious Wegovy side effects, such as pancreatitis or gallbladder problems, are rare but need urgent medical attention. If symptoms persist or worsen, speak to one of our pharmacists for advice.

Who can use Wegovy injections in the UK?

Wegovy can be prescribed for adults who: 

  • Have a BMI of 30 or above (obesity), or
  • Have a BMI of 27 or above (overweight) with a weight-related condition such as type 2 diabetes, high cholesterol or hypertension

It is not suitable for people with certain medical conditions, including a history of pancreatitis or severe gastrointestinal disease. A pharmacist consultation helps determine whether it’s safe and effective for you.

Which treatment should you choose for safe and lasting results?

Your choice of weight loss injections in the UK should depend on: 

  • Your medical history and current medicines
  • How comfortable you are with weekly or daily injections
  • Possible side effects and monitoring needs
  • Lifestyle changes you can maintain long term

While Wegovy offers an effective and convenient option for many, success also depends on balanced eating, regular activity, and ongoing support from qualified professionals.

Book your appointment with our experts at Touchwood Pharmacy to discuss safe and effective weight loss treatment options, including Wegovy and Mounjaro.

FAQs on Wegovy and Other Weight Loss Treatments

Is Wegovy the same as Mounjaro?

No, Wegovy and Mounjaro are not the same. Wegovy contains semaglutide, a GLP-1 receptor agonist, while Mounjaro contains tirzepatide, which targets both GLP-1 and GIP hormones. This dual action means Mounjaro may offer slightly greater weight loss for some people, but both are effective options depending on personal health factors..

Which works better for weight loss – Mounjaro or Wegovy?

Clinical data shows that both can help achieve significant weight loss when combined with lifestyle changes. Some studies indicate Mounjaro may lead to higher average weight loss, but individual results vary. A pharmacist consultation can help identify which treatment is more suitable based on your health and goals.

Can I switch from Wegovy to Mounjaro safely?

Switching is possible under professional guidance, but timing and dosage adjustments must be managed carefully to avoid side effects. Always speak to a pharmacist before making any changes to your treatment plan so that your transition is safe and effective.

Are Wegovy injections available in the UK right now?

Yes, Wegovy is licensed and available in the UK through private pharmacies and specialist weight management services. Supply can vary depending on demand, so checking availability before booking your appointment is recommended.

What are the main side effects of Wegovy compared with other injections?

Some common Wegovy side effects include nausea, constipation, and fatigue, which are usually mild and temporary. Mounjaro and Saxenda may cause similar effects because they act on related hormone pathways. Our pharmacist can advise how to reduce discomfort during treatment.

Can Wegovy be used without diabetes?

Yes, Wegovy can be prescribed for weight management even if you do not have diabetes. It is licensed in the UK for adults with obesity or those overweight with a weight-related condition, provided it is clinically appropriate after a pharmacist assessment.