Planning a trip to parts of Africa or South America often means thinking about more than just flights and itineraries. With 27 African countries and 13 Latin American countries currently classed by WHO as yellow fever risk areas, many travellers choose or are required to get protected before they go.
The yellow fever vaccine is a reliable way to prevent infection, but like any vaccination, it can cause certain reactions. Understanding these possible side effects helps you feel prepared and reassured ahead of your journey.
What Are the Common Side Effects of the Yellow Fever Vaccine?
Common side effects of the yellow fever vaccine are usually mild and settle on their own within a few days. They are a normal response to the vaccine and show that your immune system is building protection.
What mild symptoms might you notice after vaccination?
Most people experience only minor issues such as:
- Low-level fever
- Headache
- Muscle aches
- Tiredness
- Pain or swelling at the injection site
These reactions are usually short-lived. They tend to peak within 24 hours and ease without treatment.
How long do common reactions last?
Mild yellow fever vaccine side effects often last between one and three days. Rest, fluids, and simple pain relief if suitable for you can help ease discomfort.
What Are the Less Common Yellow Fever Vaccine Reactions?
Less common reactions can appear in a small number of people but are still generally manageable. They do not affect most travellers.
What symptoms are considered less common?
These may include:
- General feeling of being unwell
- Mild rash
- Temporary swelling of glands
These reactions are usually mild and settle without further support.
Do these symptoms require support?
Most of these reactions improve quickly, but you can speak to our pharmacists if symptoms last longer than expected or feel unusual for you.
Are There Any Serious or Rare Reactions to the Yellow Fever Vaccine?
Serious reactions to the yellow fever vaccine are rare, but it is important to be aware of them. These reactions are linked to how your immune system responds to the vaccine rather than the yellow fever virus itself.
What rare reactions should you be aware of?
Serious reactions may include:
- Severe allergic response
- Neurological issues such as inflammation of the brain
- Problems affecting internal organs
These complications are extremely rare. They are more likely to occur in people with specific medical conditions, weakened immune systems, or those over 60.
When should you seek urgent help?
Seek immediate medical support if you notice:
- Difficulty breathing
- Severe rash
- Confusion or changes in behaviour
- Yellow fever symptoms such as high fever, vomiting or jaundice appearing after recent travel
While these reactions are very uncommon, prompt action keeps you safe.
Who Is More Likely to Experience a Strong Yellow Fever Vaccine Reaction?
Not everyone is at equal risk. Some groups have a higher chance of experiencing stronger reactions and may require a personalised travel health assessment.
Who might need extra care?
You may need additional advice if you:
- Are over 60
- Have an immune condition
- Are pregnant or breastfeeding
- Have a history of severe allergies
- Have had a previous reaction to a vaccine
Our pharmacists will assess your suitability before giving the yellow fever vaccine and may recommend an exemption certificate if the vaccine is not safe for you.
How Can You Reduce the Chance of Side Effects?
There is no guaranteed way to prevent reactions, but a few steps can make the experience smoother.
What helps minimise discomfort after vaccination?
Try the following:
- Keep the arm relaxed and mobile.
- Avoid intense exercise immediately after the jab.
- Use a cool compress on the injection area.
- Drink plenty of water.
- Rest if you feel tired.
If you are unsure whether your reaction is normal, our pharmacists can provide personalised reassurance.
Where Can You Get Safe Yellow Fever Vaccination Guidance in the UK?
Getting the vaccine from a trusted travel health clinic ensures you receive the correct dose, proper screening, and the right certification for your destination. Our pharmacists are trained in travel vaccination and can guide you through possible yellow fever vaccine side effects, what to expect, and how to prepare for your trip.
Book your appointment with our experts at Touchwood Pharmacy for safe and reliable travel vaccination support.
FAQs
Can the yellow fever vaccine make you feel unwell after the jab?
Yes, some people feel slightly unwell after the yellow fever vaccine. This can include tiredness, low fever, headache or mild body aches. These symptoms usually settle within a few days and do not affect your long-term protection.
How soon do yellow fever vaccine side effects start?
Most side effects start within 24 hours of the injection. Some people may notice delayed reactions around four to ten days later, which can include mild fever or general fatigue. Both are expected responses to the vaccine.
Is it normal to have a swollen arm after the yellow fever vaccine?
Yes, swelling or soreness at the injection site is very common. It is caused by your immune system responding to the vaccine. The discomfort normally improves within two to three days. A cool compress and gentle movement of the arm can help.
Are older adults more likely to have a strong reaction to the yellow fever vaccine?
Adults over 60 have a slightly higher risk of stronger reactions, including rare complications. This is why a travel health assessment is recommended before the vaccine. Our pharmacists will review your medical history to check if the vaccine is safe for you.
Can you get yellow fever symptoms from the vaccine itself?
No, you cannot get yellow fever from the vaccine. The vaccine contains a weakened form of the yellow fever virus that cannot cause the disease. However, it can trigger mild flu-like symptoms that may feel similar but are not the actual infection.
What should I do if my side effects last longer than expected?
If your symptoms last more than a few days, feel unusual for you, or worsen with time, you should seek advice promptly. Our pharmacists can help you understand whether your reaction is typical or if you need further assessment.
